NASA's Astrophysics Archives preserve many terabytes of multiwavelength images, catalogs, and spectra. While many astronomers are familiar with the web tools that are convenient for searching and visualizing these data, programmatic interfaces through Python are increasingly in demand. This hands-on workshop will introduce participants to the programmatic data access tools available and the tutorial notebooks NAVO offers. We will describe science scenarios that combine multiwavelength data from the HEASEARC, IRSA, NED, and MAST that participants will then be encouraged to work through themselves. Workshop organizers will be available to help participants complete them and/or adapt them for custom projects.